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Human papillomavirus (HPV) vaccination programmes do not result in an increased occurrence of HPV strains that are not dealt with by the inoculation, a study has indicated.
Research led by scientists at the UNC Lineberger Comprehensive Cancer Center, which involved the analysis of 2,228 Kenyan men, revealed international healthcare projects aimed at immunising people against particular strains of HPV did not result in viral-type competition, or when different types of a certain virus compete with each other to attain dominance in the populace.
This study and a follow-up investigation were published in the Journal of Infectious Diseases and present the first epidemiological statistics on type-specific links between the prevalent types of HPV and further acquisition of other HPV strains.
Although the research only involved males who had not been vaccinated, senior study author Dr Jennifer Smith pointed out the investigation reveals different types of HPV generally act independently of each other.
This is of "potential importance", she declared, arguing it reveals that HPV-type replacement is unlikely to happen after young male adolescents have been vaccinated in large-scale inoculation schemes.
Dr Smith asserted that there is "no evidence" that different HPV types compete with each-other among high-risk Kenyan males.
Currently-available HPV vaccinations protect people against HPV 16 and 18, which are the two most common types of the virus that can cause women to develop cervical cancer.
According to the World Health Organisation, these two viruses are responsible for around 70 per cent of all international cervical cancer cases, while 99 per cent of all incidences of this type of cancer are linked to genital infection with some form of HPV.
Further data will be required to determine if HPV acquisitions differ between men with different strains of the virus and men who have not been infected with HPV.
The scientists claimed in the long-term, this could impact the potential for the replacement of HPV-types after a populace has been vaccinated.
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